Stiff Person Syndrome

2022 - 12 - 9

Celine Dion Celine Dion

Post cover
Image courtesy of "The Indian Express"

What is 'Stiff-Person Syndrome', the rare neurological disorder ... (The Indian Express)

"While we're still learning about this rare condition, we now know that this is what has been causing all of the spasms that I've been having," the singer ...

[muscle](https://indianexpress.com/article/lifestyle/fitness/how-to-build-muscle-tips-fitness-7784059/) spasms are the norm and superimposed upon baseline muscle stiffness. [brain ](https://indianexpress.com/article/lifestyle/health/lifestyle-changes-to-build-the-healthiest-brain-8099833/)and spinal cord. [muscle](https://indianexpress.com/article/lifestyle/health/muscle-strength-mass-loss-ageing-health-8222525/) stiffness and spasm that preferentially affects axial (back and abdominal) muscles, neurological experts noted. 70 per cent of patients with GAD antibodies have [diabetes ](https://indianexpress.com/article/lifestyle/health/5-lifestyle-tips-risk-of-diabetes-weight-physical-activity-sugar-8298388/)mellitus as a comorbidity. In patients with paraneoplastic Stiff Person Syndrome, identification and eradication of the underlying malignancy can alleviate symptoms. It is commonly associated with affective symptoms such as anxiety, phobias and The disorder has left her with difficulties in [walking ](https://indianexpress.com/article/lifestyle/fitness/walking-exercise-strength-training-yoga-rujuta-diwekar-8118751/)and singing due to which she will be unable to take part in planned shows in the UK and Europe next year. “In the classical form of the disease, the initial symptom is typically painful muscle stiffness in the lumbosacral and abdominal regions. But symptoms can also include a person having greater sensitivity to noise, touch, and emotional distress,” Dr Gupta said. It frequently affects [women with a median onset of 35 to 40 years of age](https://indianexpress.com/article/lifestyle/health/lifestyle-changes-women-40s-expert-tips-health-7981725/),” Dr Mohan Krishna J, Consultant Neurologist, Yashoda Hospitals, [Hyderabad](https://indianexpress.com/section/cities/hyderabad/) said. According to experts, this syndrome can manifest itself in many ways. “The malignancies associated with stiff-person syndrome are

Post cover
Image courtesy of "India Today"

What is Stiff-person Syndrome, severe condition Celine Dion suffers ... (India Today)

In an emotional video, Celine Dion revealed she has Stiff-person Syndrome, a rare neurological disorder. This illness results in stiffness and spasms in the ...

It disrupts the normal pathways of communication between the brain and the muscles. Anti-anxiety medications, muscle relaxers and pain relievers may be a part of the treatment. A person suffers from stiffness in these muscles and becomes sensitive to noise, touch and emotional distress. Recently, I've been diagnosed with a very rare neurological disorder called stiff-person syndrome which affects something like one in a million people," Dion said in the Instagram clip, addressing her fans both in English and French. [National Institute for Neurological Disorders](https://www.ninds.nih.gov/health-information/disorders/stiff-person-syndrome), Stiff-person syndrome (SPS), also known as Moersch-Woltman syndrome, is a rare, progressive neurological disorder that targets the muscles in the torso region, the arms and the legs. In an emotional video, Celine Dion revealed she has Stiff-person Syndrome, a rare neurological disorder.

Post cover
Image courtesy of "Hindustan Times"

Stiff-person Syndrome: What is Celine Dion's 'human statue' illness (Hindustan Times)

Celine Dion Stiff-person Syndrome: Celine Dion said she had been suffering from health problems "for a long time". | World News.

While some patients remain stable over the years, others' can worsen with time. In a five-minute video posted on Instagram in French and English, an emotional Celine Dion said she had been suffering from health problems "for a long time". It usually occurs in about one in every one million people, and affects the central nervous system. What causes the Stiff-person Syndrome? Stiff-person Syndrome, also known as SPS and Moersch-Woltman syndrome, is a rare autoimmune movement disorder. What is Stiff-person Syndrome?

Post cover
Image courtesy of "NDTV"

Celine Dion Has Stiff-Person Syndrome. What It Is And How It Is ... (NDTV)

Singer Celine Dion paused all of her performances after she was diagnosed with Stiff Person Syndrome, bringing attention to this rare disorder.

There is no cure for Stiff Person Syndrome, and the cause is unknown. While the first case was called stiff man syndrome, the patient was actually of a woman. The prognosis is different for every person because symptoms can vary widely.

Post cover
Image courtesy of "Economic Times"

What is stiff-person syndrome, a rare neurological condition Celine ... (Economic Times)

Celine Dion claims the disease has harmed her vocal chords and has hampered her ability to sing. Know more about this rare neurological condition.

[Celine](/topic/celine)stated in her emotional video, this very rare condition affects one in a million people and damages the body's central nervous system. An emotional Celine [Dion](/topic/dion)stated in a five-minute video released on Instagram in French and English that she has been suffering from health concerns "for a long time”. Celine said that she had neurological issues in her everyday life that prevented her from using her vocal chords like she used to.

Post cover
Image courtesy of "മാതൃഭൂമി"

'പാടാൻ കഴിയാത്ത വിധം ഈ രോഗം ... (മാതൃഭൂമി)

Content Highlights: celine dion suffers from stiff-person syndrome · Share this Article · സ്‌ക്രീനില്‍ കണ്ടതിനേക്കാള്‍ വലിയ ...

Post cover
Image courtesy of "Smithsonian"

What Is Stiff Person Syndrome? Celine Dion Announces Diagnosis ... (Smithsonian)

The rare neurological disease affects about one to two people in a million.

Post cover
Image courtesy of "TIME"

What It's Like to Live With Stiff Person Syndrome (TIME)

twIn an emotional social-media video posted Dec. 8, singer Celine Dion informed fans that she has been diagnosed with a rare neurological disease called ...

Two years and about 20 doctors later, a neuromuscular specialist finally diagnosed her with stiff person syndrome, based on her symptoms and the fact that Valium was the only intervention that seemed to alleviate some of the pain. While it’s not clear what triggers the syndrome in people who don’t show signs of immune system disorders beforehand, one theory is that stiff person syndrome could be the immune system’s very early response to cancer. She developed a blood clot from the port required for the procedure and couldn’t continue. The monoclonal antibody medication rituximab (Rituxan), which is prescribed to treat certain autoimmune diseases and cancers, can also help. [National Institute of Neurological Disorders and Stroke](https://www.ninds.nih.gov/health-information/disorders/stiff-person-syndrome), stiff person syndrome has similarities to autoimmune disease, in which the body’s immune system attacks its own cells. Currently, the treatments for the condition include muscle relaxants and anti-convulsant medications, which can alleviate some of the symptoms of the condition, as well as IV antibody treatments that try to reset the immune system to dial down its attack on the body’s own cells. “The body may be sensing early cancer and generates an immune response to those early cancer cells with antibodies that cross react with the nervous system. “The inhibitory signals become weaker and weaker, and the excitatory signals start to take over, contracting the muscles uncontrollably.” People with the condition often experience muscle spasms in the trunk, arms, or legs and become more sensitive to noise and touch. “To this day when I see doctors for something else and they see that I have stiff person syndrome, I cannot tell you how many [of them] have said, ‘What is that? After a visit to the emergency room, doctors gave her a Valium drip to address the pain, which helped, but she still didn’t know why she was experiencing spasms. “Something in the software goes wrong, and the inhibitory system starts to malfunction,” says Dr. “I’ve been dealing with problems with my health for a long time…we now know this is what’s been causing all of the spasms that I’ve been having,” said Dion, who is 54.

Post cover
Image courtesy of "Healthline"

Celine Dion and Stiff-Person Syndrome: The Signs, Symptoms, and ... (Healthline)

Celine Dion has revealed that she has been diagnosed with stiff-person syndrome (SPS), a rare neurological disorder that causes muscle stiffness and painful ...

“We found that 67% of the patients improved,” he said. The average follow-up period in the study was 3.3 years. Most people with SPS have higher levels of GAD antibodies. “And we’re a large, dedicated national referral center — so hopefully that gives perspective on the relative rarity of this condition.” “But in general, for most SPS patients, symptoms slowly progress over time.” We also use some other immunosupressive medications off-label,” she said. “Those of us in autoimmune neurology who treat patients have been trying — and will continue trying — to attract funding agencies to work with us to study SPS,” she said. [podcast](https://podcasts.apple.com/us/podcast/neurology-podcast/id266288159?i=1000578454672) of the American Academy of Neurology that his recent study showed that IVIg is beneficial for patients with SPS over the long term. That’s where IVIg [intravenous immune globulin therapy] falls. [treatment](https://rarediseases.org/rare-diseases/stiff-person-syndrome/) for SPS involves a two-pronged approach, with treatments targeting symptom management, and treatments targeting the immune system. “And even then, most people with a history of these more common autoimmune conditions will never have a family member who is diagnosed with stiff person syndrome,” she added. [1 in a million people](https://rarediseases.org/rare-diseases/stiff-person-syndrome/), with the condition twice as common in women than in men.

Post cover
Image courtesy of "Economic Times"

Celine Dion gets diagnosed with Stiff Person Syndrome. See what it is (Economic Times)

Stiff Person Syndrome is gaining attention in the media after Celine Dion was diagnosed with the incurable neurological condition.

As of now, there is no available cure for Stiff Person Syndrome. According to reports, it could be an autoimmune disease in which the central nervous system is attacked by the body, causing damage to the nerve cells. The most common symptom is muscle spasms, which can come anytime unexpectedly.

Explore the last week